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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure-function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting "What We Don't Know," introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

 

 

 

 

 

 

/ AUS DEM INHALT: / / /

 

 

PART I INTRODUCTION TO THE CELL 1

 

Chapter 1 Cells and Genomes 1

 

Chapter 2 Cell Chemistry and Bioenergetics 43

 

Chapter 3 Proteins 109

 

 

 

PART II BASIC GENETIC MECHANISMS 175

 

Chapter 4 DNA, Chromosomes, and Genomes 175

 

Chapter 5 DNA Replication, Repair, and Recombination 237

 

Chapter 6 How Cells Read the Genome : From DNA to Protein 299

 

Chapter 7 Control of Gene Expression 369

 

 

 

PART Ill WAYS OF WORKING WITH CELLS 439

 

Chapter 8 Analyzing Cells, Molecules, and Systems 439

 

Chapter 9 Visualizing Cells 529

 

 

 

PART IV INTERNAL ORGANIZATION OF THE CELL 565

 

Chapter 10 Membrane Structure 565

 

Chapter 11 Membrane Transport of Small Molecules and the Electrical Properties of Membranes 597

 

Chapter 12 Intracellular Comp artments and Protein Sorting 641

 

Chapter 13 Intracellular Membrane Traffic 695

 

Chapter 14 Energy Conversion: Mitochondria and Chloroplasts 753

 

Chapter 15 Cell Signaling 813

 

Chapter 16 The Cytoskeleton 889

 

Chapter 17 The Cell Cycle 963

 

Chapter 18 Cell Death 1021

 

Chapter 19 Cell Junctions and the Extracellular Matrix 1035

 

 

 

PART V CELLS IN THEIR SOCIAL CONTEXT 1035

 

Chapter 20 Cancer 1091

 

Chapter 21 Development of Multicellular Organisms 1145

 

Chapter 22 Stem Cells and Tissue Renewal 1217

 

Chapter 23 Pathogens and Infection 1263

 

Chapter 24 The Innate and Adaptive Immune Systems 1297

 

 

 

Glossary G: 1

 

Index 1: 1

 

Tables T he Genetic Code, Amino Acids T: 1