Aktion	Zweigstelle	Standorte	Status	Frist	Vorbestellungen
Vorbestellen	Zweigstelle: 07., Urban-Loritz-Pl. 2a	Standorte: NN.BA FS.E Pass / College 6a - Englisch	Status: Entliehen	Frist: 06.12.2024	Vorbestellungen: 0

(Verlagstext)

Ever since the International Human Genome Project achieved its extraordinary goal of sequencing and mapping the entire human genome, represented by approximately 3 billion base pairs, with its far-reaching implications for understanding the causes of human genetic disorders and their diagnosis, progress in the field has not slowed down.

 

In the fifth edition of the bestselling Color Atlas of Genetics, readers will be rewarded with a complete and current overview of the field, with an emphasis on the interface between fundamental principles and practical applications in medicine and the role of signaling pathways in causing diseases.

 

Using the acclaimed Flexibook format designed for easy visual learning and retention, the atlas is invaluable for students, clinicians, and scientists interested in staying up to date in this fast-evolving area.

 

New fully illustrated topics in the revised fifth edition of the atlas include:

 

An overview of disorders resulting from structural changes of the genome (genomic disorders)

Abnormal imprinting patterns

Examples of impaired signal pathways (laminopathies, fibrillinopathies, cohesinopathies, and others)

The CRISPR-Cas system

Genetic features of the aging processes

Disorders due to rearrangements of chromatin in the cell nucleus, and others

With almost 200 stunning color plates explained by concise texts on the opposite pages, including tables presenting useful data, a glossary of terms, key references, and online resources, the atlas presents clear and accessible concepts. It is an excellent refresher for investigators in any field of medicine or biology.

 

 

Table of Contents:

Introduction 1 / Fundamentals 25 / Prologue 26 / Molecular Basis of Genetics 36 / Analysis of DNA 58 / Variability of DNA 72 / Processing of DNA 80 / Eukaryotic Cells 86 / Formal Genetics 104 / Chromosomes 132 / Regulation of Gene Function 162 / Epigenetic Modifications 178 / Genetic Signal Pathways 186 / Genes in Embryonic Development 196 / Genomics 205 / Genetics in Medicine 235 / Genetic Classification of Diseases 236 / Imbalanced Homeostasis 260 / Metabolic Disorders 276 / Immune System 296 / Origins of Cancer 312 / Impaired Cell and Tissue Structure 334 / Hemoglobin Disorders 350 / Sex Determination and Differentiation 362 / Sensory Perception 370 / Chromosomal Aberrations 382 / A Brief Guide to Genetic Diagnosis 388 / Morbid Anatomy of the Human Genome 392 / Chromosomal Locations—Alphabetical List 398 / Appendix 403 / Glossary 421 / Index 447 /