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A Nobel Prize-winning neuroscientist draws on his extensive research to explore how the mind and one's individual sense of self arise from the physical matter of the brain, explaining what brain disorders can teach us about human nature.

 

A neuroscientist draws on his extensive research to explore how the mind and one's individual sense of self arise from the physical matter of the brain, explaining what brain disorders can teach us about human nature.

 

A Nobel Prizeâ€"winning neuroscientist’s probing investigation of what brain disorders can tell us about human nature

Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work continues to shape our understanding of how learning and memory work and to break down age-old barriers between the sciences and the arts.

In his seminal new book, The Disordered Mind, Kandel draws on a lifetime of pathbreaking research and the work of many other leading neuroscientists to take us on an unusual tour of the brain. He confronts one of the most difficult questions we face: How does our mind, our individual sense of self, emerge from the physical matter of the brain? The brain’s 86 billion neurons communicate with one another through very precise connections. But sometimes those connections are disrupted. The brain processes that give rise to our mind can become disordered, resulting in diseases such as autism, depression, schizophrenia, Parkinson’s, addiction, and post-traumatic stress disorder. While these disruptions bring great suffering, they can also reveal the mysteries of how the brain produces our most fundamental experiences and capabilitiesâ€"the very nature of what it means to be human. Studies of autism illuminate the neurological foundations of our social instincts; research into depression offers important insights on emotions and the integrity of the self; and paradigm-shifting work on addiction has led to a new understanding of the relationship between pleasure and willpower.

By studying disruptions to typical brain functioning and exploring their potential treatments, we will deepen our understanding of thought, feeling, behavior, memory, and creativity. Only then can we grapple with the big question of how billions of neurons generate consciousness itself.

Contents: What brain disorders can tell us about ourselves -- Our intensely social nature : the autism spectrum -- Emotions and the integrity of the self : depression and bipolar disorder -- The ability to think and to make and carry out decisions : schizophrenia -- Memory, the storehouse of the self : dementia -- Our intrinsic creative capability : brain disorders and art -- Movement : Parkinson's and Huntington's diseases -- The interplay of conscious and unconscious emotion : anxiety, post-traumatic stress, and faulty decision-making -- The pleasure principle and freedom of choice: addictions -- That's all, folks -- Sexual differentiation of the brain and gender identity -- Consciousness : the great remaining mystery of the brain -- Conclusion : coming full circle.