How does a single cell develop into myriad different specialised cell types, control the organization of these different cells into tissues and organs, and ultimately form an unimaginably complex living organism such as a human? Furthermore, how is it possible for some adult animals, but not others, to regenerate fully functioning limbs?
Principles of Development opens up the fascinating field of developmental biology to those wanting to understand the answers to questions such as these. Cutting edge science is explained clearly and succinctly and is richly illustrated with a variety of custom drawn figures, animations, and links to online movies that show development happening in real time.
The emphasis throughout the text is always on the key principles of development - the underlying processes shared by diverse groups of organisms. This focus on principles provides a framework on which a richer understanding of specific topics can be built. Moreover, extensive pedagogical support is provided, both in the book and online, making this text the complete package for those studying developmental biology.
-Test your understanding with multiple choice questions and answer guidance to long-answer questions from the book
-Gain a three dimensional perspective of development by watching the movies of developing model organisms
-View the signalling pathway animations to see these complex processes broken down step by step
-Expand your knowledge and guide your studies with the suggested web activities
- Examine and interpret raw data obtained by Cheryll Tickle and members of her laboratory and presented in silico
For registered adopters of the text:
-Download the figures from the book to use in lectures and hand-outs
-Help your students delve into the research literature with the Journal Club-Download the test bank or import it into your VLE
-PowerPoint of In silico practicals to use in class
An extremely well written book that explains the major developmental concepts and processes in a clear and concise manner, approachable to students. I find the provision of in silico practical activities and on-line journal club supported by lecturer notes extremely helpful for my teaching. Together with on-line MCQs, I use these to test the students' knowledge and help them develop deep understanding and enthusiasm for the subject. Dr Aida Rajic, University of Suffolk
Aus dem Inhalt:
Preface viii / 1 The Foundations of Biochemistry 1 // I STRUCTURE AND CATALYSIS 45 / 2 Water 47 / 3 Amino Acids, Peptides, and Proteins 75 / 4 The Three-Dimensional Structure of Proteins 115 / 5 Protein Function 157 / 6 Enzymes 187 / 7 Carbohydrates and Glycobiology 241 / 8 Nucleotides and Nucleic Acids 279 / 9 DNA-Based Information Technologies 319 / 10 Lipids 361 / 11 Biological Membranes and Transport 387 / 12 Biosignaling 437 // II BIOENERGETICS AND METABOLISM 491 / 13 Bioenergetics and Biochemical Reaction Types 495 / 14 Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway 533 / 15 Principles of Metabolic Regulation 575 / 16 The Citric Acid Cycle 619 / 17 Fatty Acid Catabolism 649 / 18 Amino Acid Oxidation and the Production of Urea 675 / 19 Oxidative Phosphorylation 711 / 20 Photosynthesis and Carbohydrate Synthesis in Plants 755 / 21 Lipid Biosynthesis 811 / 22 Biosynthesis of Amino Acids, Nucleotides, and Related Molecules 859 / 23 Hormonal Regulation and Integration of Mammalian Metabolism 907 // III INFORMATION PATHWAYS 955 / 24 Genes and Chromosomes 957 / 25 DNA Metabolism 987 / 26 RNA Metabolism 1035 / 27 Protein Metabolism 1077 / 28 Regulation of Gene Expression 1127 / Abbreviated Solutions to Problems AS-1 / Glossary G-1 // Index 1-1
Lewis Wolpert, Cheryll Tickle, Alfonso Martinez Arias
Oxford, Oxford University Press
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sixth edition, XXIVI, 741 Seiten : Illustrationen
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